Down+Syndrome

=How is down syndrome a genetic disorder? Down Syndrome is one of the most serious chromosomal genetic diseases. It happens due to errors during the cell division. When meiosis happens there is an important possibility of undesirable events to happen. More specifically, during meiosis, the pairs of chromosomes split up and go to different spots. These spots will be the starting point for the creation of the nucleus of the daughter cells. In some abnormal situations, one pair of chromosomes doesn’t split. As a result, the resulting nucleuses carry 22 and 24 chromosomes but not 23. This is what we call //non disjunction// and can also happen during mitosis (duplication of somatic cells). =
 * //__Down syndrome __//**

What is Down syndrome? Down syndrome is a genetic condition in which a person has 47 chromosomes instead of the usual 46. Down syndrome occurs when there is an extra copy of chromosome 21. So some symptoms vary from person t person and can range from mild to severe symptoms. Children with Down syndrome their heads might be smaller than normal and abnormally shaped heads. The inner corner of the eyes may be rounded instead of pointed. Common signs include decreased muscle at birth, Excess skin at the nape of the neck, Flattened nose, separated joints between the bones of the skull, Single crease in the palm of the hand, Small ears, Small mouth, upward slanting eyes, Wide short hands with fingers, and White spots on the colored part of the eye. People with Down syndrome should be watched very closely. They should have Eye exam every year during infancy, Hearing tests every 6-12 months, depending on age, Dental exams every 6 months, X-rays of the upper or cervical spine between ages 3-5 years, Pap smears and pelvic exams beginning during puberty or by age 21, and Thyroid testing every 12 months. There is no specific treatment for Down syndrome. Complications with Down syndrome are Airway blockage during sleep, Compression injury of the spinal cord, Endocardits, Eye problems, Frequent ear infections and increased risk of other infections, Hearing loss, heart problems, Gastrointestinal blockage, and Weakness of the black bones at the top of the neck.

[] []